APML comprises approximately 5-8% of all Acute Myeloblastic Leukaemia (AML) and is seen mostly in middle aged individuals but can present at any age. It is amongst the most curable malignancies with survival close to 80%. Combination of all-trans-retinoic-acid (ATRA) … Continue reading →
Multiple myeloma (MM) is a neoplastic proliferation of clonal plasma cell producing a monoclonal immunoglobulin. One of the most important discoveries in the past two years was the molecular subclones in almost all patients with MM, which are present at … Continue reading →
Appropriate diagnosis of bleeding disorders needs to follow algorithm of clinical evaluation, screening test for coagulation disorders and planning further tests as per results of screening. Those haemostatic screening tests include platelet count & morphology, bleeding time (BT), prothrombin time … Continue reading →
Background: Acquired Immunodeficiency Syndrome (AIDS) is caused by the HIV virus and characterized by severe immunosuppression that leads to opportunistic infections, haematological aberrations, neoplasms and various deleterious effects on almost all the organs. It is still a major health challenge … Continue reading →
DLBCL is the most common type of adult Non-Hodgkin Lymphoma (NHL). Exact incidence of DLBCL in our county is not known but it comprises 30 40% of NHL in North America & Europe. Most recent WHO classification recognizes 13 subtypes … Continue reading →
Background: Diffuse large cell B-cell lymphoma (DLBCL) the single largest category of lymphoma, is a heterogenous group of malignant lymphomas with several morphologic features. Objective: To know the outcome and survival of subtypes of Diffuse Large B-Cell Lymphoma (DLBCL) after … Continue reading →
Amir Ali Hamidieh, Maryam Behfar Thalassaemia major (TM) is one of the most common hereditary haematologic disorder with insufficient production of red blood cells. Although regular blood transfusion relieves the complication such as anaemia, bone marrow expansion, heart failure and … Continue reading →
M B Agarwal Acute myeloblastic leukaemia (AML) is a heterogeneous disease where patients can be cured while others can succumb within a few days of diagnosis and beginning treatment. The major reason for non-curability is resistance to present treatment. Treatment … Continue reading →
Selva Titus Chacko Although all hospitalized patients are at risk for acquiring health care-associated infections (HAIs), those with malignancy- specifically solid tumours, haematological malignancies and those treated with chemotherapy and Hematopoietic stem cell transplants are at increased risk. These patients … Continue reading →
M B Agarwal Myelodysplastic syndrome (MDS) is a disease of elderly, characterized by ineffective haematopoiesis leading to cytopenia and a high risk of progression to Acute Myeloid Leukaemia (AML). Diagnosis is based on morphological assessment of blood and marrow, karyotyping … Continue reading →
