Para-Bombay Blood Phenotype with E-Beta Thalassaemia: A Rarest Case Report from Bangladesh
Tashmim Farhana Dipta, Amin Lutful Kabir, Mohammed Abdul Quader, Manjuma Rahman, Farida Parvin, Masuda Begum, Ayesha Khatun, Jolly Biswas, Salma Afrose
To our knowledge, this is the first reported case from Bangladesh of a 27-year-old-young man having ‘E-Beta thalassaemia’ along with rare ‘Para-Bombay blood phenotype’. It is also interesting to know that this ‘E-Beta thalassaemia with Para-Bombay phenotype’ is the first case reported from any country in the world.
This patient incidentally has been identified as a case of ‘Para-Bombay phenotype’ after exploring with proper blood grouping, antibody detection and salivary inhibition study. Previously he was misdiagnosed as ‘O’ RhD positive and has two events of transfusion reaction during ‘O’ positive blood transfusion.
This case emphasizes the importance of proper blood grouping incorporating cellular and serum typing including ‘O’ panel cell and Coomb’s test. Use of Anti-H reagent and secretor status detection has enormous role for identification of Para-Bombay phenotype. To confirm Para-Bombay phenotype adsorption and elution test are very important. Proper Blood group database, molecular studies, rare blood group registry and haemovigilance may solve the discrepancy and transfusion- related complications.
Correspondence: Professor Tashmim Farhana Dipta, Head of Transfusion Medicine and Clinical Haematology Department, BIRDEM General Hospital and Ibrahim Medical College, Shahbag, Dhaka, Bangladesh.
Para-Bombay Blood Phenotype with E-Beta Thalassaemia: A Rarest Case Report from Bangladesh — No Comments
HTML tags allowed in your comment: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>