Cutaneous Involvement of DLBCL: A Case Report
DLBCL is the most common type of adult Non-Hodgkin Lymphoma (NHL). Exact incidence of DLBCL in our county is not known but it comprises 30 40% of NHL in North America & Europe. Most recent WHO classification recognizes 13 subtypes DLBCL. Cutaneous B Cell Lymphomas (CBCLs) represent a unique group of lymphomas and are the second most frequent extranodal lymphomas. Biology and clinical course of cutaneous lymphoma differ significantly from the equivalent nodal lymphomas. The most aggressive form of (CBCLs) includes the primary cutaneous large B-cell lymphomas: the leg type, with poor prognosis. This type of DLBCL involves lower extremities and affected individuals are mainly of older ones. The most indolent forms comprise the primary cutaneous marginal zone and follicle centre B-cell lymphomas that despite the excellent prognosis have cutaneous recurrences very commonly. CBCLs involving trunk, scalp and face are not observed frequently.
A 60 years old male reported to E&C department of CMH Dhaka with the complaints of drowsiness and multiple nodular swelling over trunk, abdomen & scalp. Subsequently he was diagnosed as a case of cutaneous DLBCL.
Correspondence: Lt Col Dr. Md. Monirul Islam, Trainee in FCPS Part II in Haematology, CMH Dhaka.
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